Category Archives: Education

A knowledge hub for medicinal plants

Kariyat (Nilavembu) - Skullcapflavone
Kariyat (Nilavembu) – Skullcapflavone

Open source record of plants with “druggable” chemicals will help validate traditional systems

The use of Indian medicinal plants for drug discovery and therapeutics just received a boost. A database of such plants has been built by a Chennai-based team led by Areejit Samal of the Institute of Mathematical Sciences.

By documenting 1,742 Indian medicinal plants and 9,596 chemicals that plants use to thrive and ward off threats (phytochemicals), this database has the distinction of being the largest so far. This is a first step towards validating and developing traditional systems of medicine that use plant extracts.

For the repository, the scientists sourced information from several texts including those that documented tribal medicine. With supporting studies in the form of well-planned lab tests, this work has the potential to improve health care and enhance drug discovery.

Plants secrete various special chemicals to ward off predators, fight pathogens and survive in difficult situations. Some of these so-called phytochemicals have been used to prepare traditional medicines and also poisons. While there are extensive databases of phytochemicals of Chinese herbs, there has no similar work in India.

The new database, named IMPPAT (Indian Medicinal Plants, Phytochemistry And Therapeutics) brings together not just the Indian medicinal plants and their associated phytochemicals, but also the latter’s 2D and 3D chemical structures, the therapeutic use of the plants and the medicinal formulations.

Among the many challenges in building IMPPAT was in removing redundancy and standardising names and spellings that varied across the several books and documents they have referred to.

From previous work we know that natural products are made of highly complex molecules, which therefore are more likely to bind to very specific proteins unlike commercial (or synthesised) drug molecules.

“We show that phytochemicals in IMPPAT also have high stereochemical and shape complexity similar to natural product library of Clemons et al, and thus, IMPPAT phytochemicals are also expected to be specific protein binders,” says Areejit Samal. Drug molecules which are specific protein binders are likely to have fewer side-effects as they will bind specifically to their target protein.

Quest for druggability

The team analysed the features of the phytochemical structures using established “druggability” criteria.

This identified 960 potentially druggable phytochemicals of which only a small percentage showed similarities to existing FDA-approved drugs. “This offers immense potential for drug discovery,” says Dr Samal. Of the 960 phytochemicals, 14 have the highest druggability score, and one of these is Skullcapflavone I – This is produced by two plants, one of which is Andrographis paniculata, commonly known as Nilavembu or Siriyanangai. Another interesting topper is Kumatakenin, which is made by three plants including Artemisia capillaris. This plant is a close relative of Artemisia annuafrom which Nobel laureate Youyou Tu extracted the drug artemisinin which has saved the lives of many malaria patients.

“We hope to expand the links between phytochemicals of Indian medicinal plants and their target proteins, enabling application of systems biology… Our resource will help future efforts render Indian medicine evidence-based rather than experience-based,” says Dr Samal.

source: http://www.thehindu.com / The Hindu / Home> Sci-Tech> Environment / by Shubashree Desikan / Chennai – March 17th, 2018

IIT-M ties up with Australian varsity for research in metallurgy

Culmination of work by several people, says Australian Minister

The Indian Institute of Technology – Madras has tied up with the Deakin University of Australia to conduct research in metallurgy and manufacturing materials.

The Centre of Excellence in advanced materials and manufacturing was officially inaugurated on Wednesday by Philip Dalidakis, Minister for Trade and Innovation, Victoria. The partnership with Deakin University happened because of the vision of a group of people. “In 1994, Deakin University reached out to the Indian market. It was the first Australian university to come to India. Today is the culmination of a lot of work by a lot of people,” Mr. Dalidakis said.

The association with Deakin University was the oldest and most developed one, said IIT-M director Bhaskar Ramamurthi. The institute was keen that the centre take forward the relationship to research and development by including the industry and introduce “some really good innovation” that would reach the public.

The centre was housed in the research park “to constantly remind ourselves that the main goal is to achieve the outward thrust toward industry in the form of product and innovation start up,” Mr. Ramamurthi said.

B.S. Murty, professor at the Department of Metallurgical and Materials Engineering at the institute, said the aim was not only to collaborate and have a tripartite programme and work with industry, but also to conduct joint doctoral and masters programmes.

Youngsters would be trained in materials manufacturing and metallurgy and the centre would also sponsor internships. Already, an alumna had offered to sponsor 10 students for internship at the IIT-M, especially from smaller universities in and around the city, he said.

source: http://www.thehindu.com / The Hindu / Home> News> Cities> Chennai / by Special Correspondent / Chennai – March 15th, 2018

Noted historian passes away

Madurai :

Noted historian and retired history professor of MKU R Venkataraman, who used to guide heritage walks and is well known for his lectures on history of Madurai, passed away on Tuesday night due to a heart ailment. He was 85-years-old.

Madurai Chapter of INTACH mourning his death observed that he was highly knowledgeable historian who discovered many ancient Jain sites around Madurai. Though born in Hindu family, he was touched and inspired by the philosophies of Jainism. It is indeed a huge loss not only for Madurai, but for the field of studies, archaeology & history, the forum observed.

“It is a great loss and the history sessions will never be same without him”, commented K P Bharathi, consultant of DHAN’s tourism for development. At 85, Venkataraman was hale and hearty guiding the heritage walk in January but he started falling ill due to high creatinine level. He was admitted in a private hospital twenty days ago and suffered two heart attacks in the ICU. He passed away late Tuesday night and his mortal remains were cremated on Wednesday afternoon.

source: http://www.timesofindia.indiatimes.com / The Times of India / Home> News> City News> Madurai News / TNN / March 08th, 2018

The sidelined goddess of Botany

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The first Indian woman botanist, E K Janaki Ammal, ought to be more widely known for her huge contributions to science. But she remains unknown within the country and outside academic circles and even our textbooks have failed to teach our children about her glorious scientific history

: Just a fortnight before the International Women’s Day, the John Innes Centre in Norfolk, UK, announced a new scholarship for post-graduate students from developing countries in honour of an Indian woman botanist. Under the scheme, 88 applicants who wish to study plant and microbial sciences can apply in commemoration of the distinguished work and contributions of Dr.E.K.Janaki Ammal who was an international alumni of the leading research and training centre between 1940 and 1945.

A heart warming gesture from an institution abroad, but may be India should have done something similar for the country’s first home grown woman scientist, who went overseas and returned accomplished breaking every caste and gender barrier through her work.

Just take a moment to think where we would be without the inventions of this brilliant mind.

Janaki Ammal in younger days | Photo Credit: Special Arrangement
Janaki Ammal in younger days | Photo Credit: Special Arrangement

After laborious crossbreedings in the laboratory of Sugarcane Breeding Institute in Coimbatore in the 1930s, she created the indigenous variety of sweetened sugarcane that we consume today. Till then India was producing sugarcane in abundance and yet importing as they were not as sweet as the ones grown in the Far East.

During the World War II bombings in the 1940s, she continued her phenomenal research into chromosomes of thousands of species of flowering plants at the John Innes Horticultural Institute, Norfolk, where she worked with some of the best names in cytology, genetics and botany While working on the gorgeous Magnolia, she co-authored The Chromosome Atlas of Cultivated Plants with renowned biologist CD Darlington.

The magnolia saplings she planted on the Battleston Hill in Wisley continue to bloom every Spring and one of the pure white blooms is named after her, the Magnolia kobus Janaki Ammal and apparently only few nurseries in Europe have the variety today.

At a time when most Indian women did not even attend school, she received scholarship and obtained her MS from University of Michigan in 1925 and later returned as the first Indian Oriental Barbour Fellow. She remains one of the few Asian women to be conferred honorary doctorate (DSc. honoris causa) by her alma mater in 1931. There she discovered a new variety of brinjal that exhibited triploidy instead of the normal diploid, where there are two sets of chromosomes in the cells.

The flower Magnolia Kobus Janaki Ammal | Photo Credit: Special Arrangement
The flower Magnolia Kobus Janaki Ammal | Photo Credit: Special Arrangement

At the insistence of Prime Minister Jawaharlal Nehru, she returned to India in the 1950s and restructured the Botanical Society of India travelling to several remote areas of the country in search of the plant lore of the indigenous people and scouting for medicinal plants in her home State, Kerala.

A fascinating figure of the early 20th Century she was. E.K.Janaki Ammal lived a life which perhaps very few women of her time could dream of. The distinguished geneticist, cytologist, global plant geographer studied about ecology and biodiversity too and did not fear to take on the Government as an ardent environmental activist. She played an important role in the protests against the building of a hydro-power dam in Kerala’s Silent Valley in the 1970s. She made a mark with her paper on “Man’s Role in Changing the Face of the Earth” at an international symposium in Princeton in 1955 and two decades later, she was awarded the Padmashri in 1977.

With a profile like hers, Janaki Ammal never got into spotlight. If anything she fought her status as a single woman from a caste considered backward and problems with male mentorship in her field. But she proved through her work that Science knows no caste, gender or social boundaries.

Yet for her extraordinary journey from small town Thalassery to the finest institutions across the world, there is no archive related to her in India. Her papers are available only in hard copy at the Bodleian Library in Oxford, according to Vinita Damodaran, who teaches South Asian History at University of Sussex and has also published a well researched paper on “Gender, race and science in twentieth century India: E.K.Janaki Ammal and the history of science.”

Luckily, the Nikari series of talks held under the banner of ‘Manarkeni’, a Tamil research journal, brings to light the works of lesser known women in different fields. In the previous years, the focus was on women in literature and history. This year it chose science and brought the story of Janaki Ammal to the fore.

The talk delivered by S Krishnaswamy, former professor at the School of Biotechnology, Madurai Kamaraj University, highlighted various stages of Janaki’s career both in India and overseas. “Her career shows that scientists must speak their mind with social consciousness even if it means going against the policies of the government. In today’s context, it becomes necessary to bring achievers like her to the forefront,” he asserts.

Janaki Ammal must have conquered her fears and broke the glass ceiling for a rewarding career in science. “She wanted to be known only through her work. Let her work be known to all successive generations, who have much better opportunities” says Krishnaswamy.

An inspiring role model, Janaki Ammal passed away in 1984 at the age of 87 at Maduravoyal near Chennai, while working in the field laboratory of the Centre for Advanced Study in Botany, Univerity of Madras. She perhaps did not receive the acclaim she deserved but devoted herself to research, opening up a universe of possibilities. Let our children not be bereft of that knowledge. It is worth knowing and remembering leaders in science like Janaki Ammal.

source: http://www.thehindu.com / The Hindu / Home> Society / by Soma Basu / Madurai – March 09th, 2018

How a recent archaeological discovery throws light on the history of Tamil script

DECODING THE SCRIPT Archaeologists taking an estampage of the Tamil script found on the oil press. Photo: Special Arrangement   | Photo Credit: Special Arrangement
DECODING THE SCRIPT Archaeologists taking an estampage of the Tamil script found on the oil press. Photo: Special Arrangement | Photo Credit: Special Arrangement

A team of amateur archaeologists discovered an oil press belonging to 10th century C.E. near Andipatti with a Tamil script. It is one of the earliest Tamil inscriptions to be found in this region.

When R. Udhayakumar a research scholar of Government Arts College, Melur got a call from Tamil teacher Balamurugan from Andipatti about an age-old stone structure that resembles a grinder, he did not take it seriously. But when he along with his friend C. Pandeeswaran, who is also a research scholar from Madurai Kamaraj University, visited the spot he came to know that it was not a grinder but a ‘chekku’ (oil press, used to extract oil).

“When I went there I could locate the oil press neatly carved on the rocky bed of a wild brook, which now runs dry,” says Udhayakumar. “The place is very near to the revenue department office in Andipatti and many villagers say that they had seen water flowing through when there was flood some years ago,” he says.

The team took estampage of the inscription and it was brought to C. Santhalingam, secretary, Pandyanadu Centre for Historical Research, to decipher. “Based on the inscription, the oil press belongs to 10th century CE. It is written in Tamil script and says that the oil press was installed by one Kudiyaan Thevan for common purpose. Also, the inscription throws light on the village and its geographical location. The place is inscribed as ‘Thenmutta Naatu Kannimangalam’. Probably, there should have been many Kannimangalams and this one is located in Thenmutta Naadu, a geographical unit Kings followed in those periods. Places in and around Andipatti region were called as Thenmutta Naadu and there are references,” says Santhalingam.

Though discovering an oil press is nothing new in these parts as the team identified similar one in Chitharevu near Periyakulam six months ago. What made the discovery significant is the Tamil script on it. Earlier ones had Vattezhuthu script. “King Raja Raja Chola I ruled Pandya Kingdom during 10th century CE and he introduced Tamil script here as he was quite adept in it. Also, he did not know to read Vattezhuthu. Hence, he recorded all his documents in Tamil script and encouraged the people to learn the same. The king had even translated Vattezhuthu script to Tamil script evident from the Kutralanathar Temple inscriptions in Courtallam. Comparatively, Tamil script was easy to learn than Vattezhuthu and public patronage grew that saw the decline of Vattezhuthu. Gradually, Tamil script gained prominence,” he says.

Tamil script was widely practiced and popularised by Pallavas who had inscribed on the door jambs of sanctum santorum of temples in Thanjavur. “In fact, it was Pallavas who helped Cholas learn the script. Most of the inscriptions after Chola rule in Pandya kingdom are in Tamil script,”

Early inscriptions found in Pandya Kingdom are in Tamil Brahmi and Vattezhuthu scripts. Even in Irukkandurai, a medieval period port city in Radhapuram Taluk in Tirunelveli, which was discovered by Santhalingam and his team last year, there are 25 inscriptions. Of them, only three belonged to early Pandyas and they are in Vattezhuthu whereas the rest are in Tamil script and they talk about the prowess of Rajendra Chola I.

The oil press found in Andipatti goes into history as the symbol of transition from Vattezhuthu to Tamil script.

source: http://www.thehindu.com / The Hindu / Home> Society / by T. Saravanan / Madurai – February 21st, 2018

Two T.N. students’ artwork finds place in NASA calendar

NASA had received about 3,000 entries from 193 countries

Two students from Shree Vidhya Mandhir, Pushpathur, Dindigul district won the NASA’s 2018 Commercial Crew Program Calendar Art Contest.

The artworks of students Kaviya B.J. and K. Selva Sreejith of Class VI were among the 12 selected from about 3,000 entries submitted by children in the age group of 4-12 years from 193 countries. Their work will be printed in the 2018 calendar of NASA will be sent to the International Space Station.

While Kaviya drew an organic space garden, Sreejit’s artwork was titled ‘What would you take from home’, where he drew an astronaut who brought along his daughter, dog and all his favourite possessions to the space shuttle. The winning students will receive a gift package from NASA. The students were able to participate in the contest because of a tie-up between the school and Imageminds, a digital media training centre.

source: http://www.thehindu.com / The Hindu / Home> News> Cities / by Staff Reporter / Chennai – January 17th, 2018

Church Park’s centenary

Oh my god, I can’t believe you’ve actually come!” exclaimed a middle-aged woman as she hugged her friend. All around, there was non-stop chatter and raucous laughter. The excitement was palpable at the school auditorium as young and old merged to form a timeless mosaic. For long moments, the alumni who had gathered seemed to bring the past alive, looking every bit the giggly schoolgirls they once were. The occasion was the celebration of 100 years of their beloved alma mater, the Sacred Heart Matriculation School, Church Park.
As a significant part of the centenary celebrations, the alumni association brought out a coffee-table book, The School in the Park: 100 years of Church Park.’ The contributions of several past students were put together and edited by S Muthiah, Chennai chronicler.

The book traces the beginnings of the Church Park story that had its roots in County Cork, Ireland, where Nano Nagle founded the Presentation order of nuns in 1771. Some of the nuns came to India in 1842 to set up schools in Madras, Kodaikanal, Delhi and Rawalpindi.

Uma Narayanan, past pupil and principal writer of the book, said that they used old log books, archives from the Nehru Memorial museum and various interviews of alumni and Presentation nuns to gather information. “This was an exhilarating journey for all of us at Church Park and we are very proud of the outcome,” she said. Pointing out that he had to face many battles with “this incredible group of women,” Muthiah said tongue-in-cheek, “If I lost some of those battles, it was only because those were Church Park girls. By the end, we had formed a story of courage, a story of Irish nuns who came to India at a time when it was unthinkable.”

Kenneth Thompson, the Irish ambassador to India, received the first copy of The School in the Park: 100 years of Church Park.’ “Many of the nuns’ names are forgotten, but their sacrifices to further education in India will be cherished forever,” he said. He quoted the book and added, “It’s not the names that matter, but the school and its ethos.”

Copies of the book were presented to the school’s old teachers. In the audience were Pramila Ganapathy, the first Indian student of the school, and Chandok, one of the boys who passed out of the school in the eleventh standard. There were a few celebrities too – Dr Kamala Selvaraj and Lady Darshana Sridhar, special adviser to British Prime Minister Gordon Brown. “It was here that I learnt to be confident,” said Sridhar, “the fact that I can deal with different situations with impartiality and integrity is something I owe to Church Park.”

source: http://www.timesofindia.indiatimes.com / The Times of India / News> City News> Chennai News / by Lakshmi Kumarswami / TNN / January 11th, 2009

Workshop showcases variety in architectural themes

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Exhibition, discussions held as part of Portfolio18

Deft handwork, good imagination and perfect pictorial finish were the highlights of Portfolio18, an architectural workshop organised at the Lalit Kala Akademi in the city. The exhibition of the works of students pursuing architecture was organised by the Chennai Architecture Foundation.

The three-day event, which was inaugurated on Friday, showcased the works of students from 11 architecture colleges from across the State. The displays, some of which were thesis works by students, included representations of the topography of villages, architectural works of real estate layouts in 2D formats and printed T-shirts. Hundreds of enthusiastic visitors took a keen interest in the displays.

A spokesperson of CAF said the exhibition, which was not a competition, would be an annual event. Apart from the exhibition, the event also had open house discussions where speakers talked about architecture and architectural education, the ground reality in academic institutions and the nature of work produced, and experiments undertaken in academic studios across the State.

In the open house session, students spoke on the theme ‘If I were to learn design, how would I learn?’.

Another segment was ‘College in Focus’, where representatives of institutions shared their ideas and approaches to education.

The event had a variety of events of value to students of architecture, as well as aspiring students and their parents.

source: http://www.thehindu.com / The Hindu / Home> News> Cities / by Staff Reporter / Chennai – January 09th, 2018

Architecture exhibition from Friday

The city will host an architecture exhibition called ‘Portfolio 18’ to showcase the work of students and to create a platform for various stakeholders to discuss about architecture education.

The first edition organised by the Chennai Architecture Foundation would be held at Lalit Kala Akademi from January 5 to 7. While the main focus of the three-day event is the architecture exhibition called ‘Pin Up,’ which will display the academic works of 11 prominent colleges in the State, there is also ‘College in Focus,’ where ideas about architecture could be shared. A panel discussion will be held among students and faculties.

Works from the CARE School of Architecture, Hindustan University, Rajalakshmi School of Architecture and VIT University would be on display.

A spokesperson of CAF said the idea to launch ‘Portfolio 18’, an annual exhibition, is to give an opportunity for students, faculty and institutions to share their experiences and thoughts and to remove certain misgivings of architecture education.

source: http://www.thehindu.com / The Hindu / Home> News> Cities> Chennai / by Staff Reporter / Chennai – January 02nd, 2018

Call to undertake research in ancient Tamil music

Madurai :

Poet N S Sundararaman of Dharumai Aadheena mutt has said that the names of many renowned Shiva temples, revered in Thevaram (garland of divine songs praising Lord Shiva), were sanskritised in the past and the same fate should not befall Pannisai (ancient Tamil music and a predecessor of Carnatic music).

He further urged the Tamil Isai Sangam to undertake research in Pannisai. He was speaking at the Tamil Isai Sangam’s silver jubilee anniversary celebrations on Monday. The Sangam honoured its octogenarian trustee S Mohangandhi, also a former income tax officer on the occasion. Mohangandhi was a student of the first batch of Thevaram class and was praised for his untiring efforts to promote it for 25 years.

Since 1992, the Tamil Isai Sangam, functioning at the Raja Muthiah Mandram, has been conducting free music class on Thevaram on its premises and more than 2,000 people have studied there so far.

Sundararaman said that learning of Thirumurai (Shaiva literary works, twelve in number) will help one in many ways. “Thirumurai will uplift humans. It will change the thinking of chicanery and will help one to attain self-realisation. People belonging to Nagarathaar clan have contributed much to spreading Tamil Isai. The Tamil Isai Sangam needs to do research in Pannisai,” Sundararaman said.

Former Income Tax commissioner of Madurai S Sankaralingam who presided over the function said “One who wishes to see progress in life needs to learn Thevaram and read Thirumurai.” Trustee Thu. Meikandaan said “Thevaram music will help better functioning of brain.” Tamil Isai Sangam secretary P R Chockalingam and treasurer R M Somasundaram offered felicitations. V S Janaranjani welcomed the gathering. A G Sankar proposed a vote of thanks. A women’s troupe also sang Thevaram at the function.

source: http://www.timesofindia.indiatimes.com / The Times of India / News> City News> Madurai News / TNN / December 26th, 2017